Journal: Quantitative Imaging in Medicine and Surgery
Article Title: Feasibility of shortening the 18 F-FDG Patlak scan time in a high-sensitivity short-axial field-of-view positron emission tomography-computed tomography system for oncological studies using deep learning denoising algorithms
doi: 10.21037/qims-2025-1757
Figure Lengend Snippet: Four dynamic whole-body Patlak imaging protocols were derived from a dual-injection FDG-PET scanning method. The initial injection occurred at time zero, with the second injection being administered approximately 80 min later. The 41 to 75 min interval was used for Patlak analysis, while the remaining periods (0–6, 7–40, and 80–86 min) were designated for generating various types of AIF. AIF, arterial input function; FDG, fluorodeoxyglucose; PET, positron emission tomography.
Article Snippet: The external datasets consisted of 510 participants with a 50% and 100% full-dose WB FDG-PET scan collected from the Ultra-low Dose PET Challenge ( https://ultra-low-dose-pet.grand-challenge.org ), which includes different levels of low-count FDG-PET and full-dose FDG-PET scans acquired from the Biograph Vision Quadra (Siemens Healthineers) and the uEXPLORER (United Imaging Healthcare, Shanghai, China) scanners.
Techniques: Imaging, Derivative Assay, Injection, Positron Emission Tomography